Modelagem comparativa de proteínas

🔬 Discover the Intricacies of Protein Modeling with Dr. Diego Mariano 🔬

Course Title: Mastering Protein Modeling through Structural Bioinformatics

🚀 Course Headline: Aprenda como criar modelos de proteínas usando programas de Bioinformática Estrutural!

Introduction to Proteins and Their Structural Importance: Proteins are the workhorses of life, performing a myriad of functions within all organisms. Unlocking the secrets of their three-dimensional structures is crucial for understanding their biological roles and potential applications. However, experimental methods to determine these structures can be costly and time-consuming. This is where computational biology steps in!

What You'll Learn:

• The Basics of Protein Modeling: Understand the importance of protein structure prediction and its applications in various fields, from basic research to drug discovery.

• Hands-On Experience with Bioinformatic Software: Gain proficiency in using two leading computational tools for protein modeling – MODELLER and SWISS-MODEL.

• Understanding the Science Behind It All: Learn the principles of homology modeling, ab initio prediction, and how to interpret and validate your models.

Course Breakdown:

• Week 1: Introduction to Protein Modeling

  • Overview of protein structure and function
  • Historical perspective on protein modeling methods
  • The role of bioinformatics in structural biology

• Week 2-3: Diving into MODELLER

  • Setting up your local environment for MODELLER
  • Step-by-step guide to building a homology model
  • Best practices and tips for model optimization

• Week 4-5: Exploring SWISS-MODEL

  • Introduction to online bioinformatics resources
  • Submitting your query sequence to SWISS-MODEL
  • Interpreting the results and assessing model quality

Why This Course?

• Economical Alternative: Reduce the costs associated with protein structure determination.
• Accessible Education: Learn from anywhere in the world without the need for specialized equipment.
• Skill Enhancement: Develop valuable skills applicable to research, academia, and industry.
• Expert Instruction: Benefit from Dr. Diego Mariano's extensive experience in computational structural biology.

What You Will Achieve:

• Master the use of MODELLER and SWISS-MODEL for protein model generation.
• Understand how to interpret and evaluate your models.
• Acquire knowledge that can be applied to a variety of research projects or career opportunities in bioinformatics, biotechnology, pharmaceuticals, and more.

Enrollment Details:

Ready to embark on this journey through the fascinating world of protein modeling? Enroll now and take your first step towards becoming an expert in computational structural biology! 🎓✨

• Start Date: [Insert Date Here]
• Duration: 6 Weeks (Part-time, self-paced)
• Format: Online with interactive assignments and forums for discussion.
• Who Should Enroll: Students, researchers, bioinformaticians, and anyone interested in the field of structural biology.

Join us and unlock the potential of computational biology! 🧬💻