Molecular biology

🌱 Introduction to the Course: "Molecular biology - A deep dive into life's code"

🚀 About the Instructor: Meet Jhanavi Ramanujam, a seasoned molecular biologist with years of experience in unraveling the complexities of life at the molecular level. Her passion for genetics and her expertise in molecular mechanisms make her an ideal guide to accompany you on this journey through the world of molecules that dictate life processes.

💎 Benefits from the Course:

• Gain a comprehensive understanding of molecular biology principles.
• Learn about the Central Dogma and its significance in biological systems.
• Explore DNA replication, transcription, and translation processes in detail.
• Discover how genes are regulated at various levels, from prokaryotes to eukaryotes.
• Enhance your knowledge of post-transcriptional and post-translational modifications.
• Understand the implications of gene regulation in both normal physiology and disease conditions.

📚 Course Structure & Topics: The course is structured into four main units, each focusing on a key aspect of molecular biology:

UNIT 1: Replication

• The Central Dogma of biology
• Mechanisms of DNA replication and semiconservative replication
• Complimentary base pairing and the role of DNA polymerases
• Understanding supercoil dynamics and DNA topoisomerase
• Exploring the replication fork and its significance
• Delving into DNA damage and repair mechanisms, including nucleotide excision repair, base excision repair, and mismatch repair systems

UNIT 2: Transcription

• Unraveling the Central Dogma of life as it pertains to transcription
• Mechanism of transcription in both prokaryotes and eukaryotes
• Initiation, elongation, and termination phases of transcription
• Post-transcriptional modifications such as capping, polyadenylation, and splicing of mRNA
• The role of inhibitors and reverse transcriptase in transcription processes

UNIT 3: Translation

• Analyzing the Genetic Code and its features
• Codon-anticodon interactions and the wobble hypothesis
• Investigating translation in prokaryotes versus eukaryotes, including energy consumption during these processes
• Understanding the initiation, elongation, and termination stages of translation
• Exploring post-translational modifications such as trimming, structural reorganization, and covalent modifications

UNIT 4: Regulation of Gene Expression

• The role of enhancers and silencers in gene expression
• Differentiating between housekeeping and invisible genes
• Understanding the one cistron-one subunit concept
• Exploring the impact of DNA organization on gene expression
• Investigating the mechanisms of histone modification in gene regulation
• Studying regulatory systems like the Lac operon in prokaryotes and the Tryptophan operon in eukaryotes

🔍 Who is this course for? This comprehensive course is designed for:

• Undergraduate and graduate students majoring in biology, molecular biology, or genetics.
• Researchers and professionals looking to deepen their understanding of molecular mechanisms.
• Educators seeking new ways to convey complex concepts in molecular biology.
• Anyone with a curious mind wishing to explore the fundamentals of life at the molecular level!

💡 Join us on this exciting journey to decode the language of life and understand how genetic information is replicated, transcribed, and translated into the proteins that make up all living organisms. With Jhanavi Ramanujam as your guide, you'll gain a profound appreciation for the complexity and elegance of molecular biology. Enroll now to embark on this transformative learning experience! 🎓✨